Inflammation, inflammation, inflammation: it’s everywhere on the net and used to sell millions of dollars worth of supplements. We are proud of the anti-inflammation properties of I LOVE H2, our molecular hydrogen supplement, but are ready to admit that diet always come first as our preferred health strategy. So we were excited to read that real science rather than marketing has narrowed down our food choices to the best anti inflammation foods on the planet.
A Menu against inflammation
A few common foods may help rein in the chronic inflammation that contributes to so many diseases. A new study by the University of Liverpool’s Institute of Ageing and Chronic Disease found that the polyphenols in onions, turmeric, red grapes, green tea and acai berries may be key to fighting the swelling.
To hone in on which foods might be most helpful in halting inflammation, scientists tested 31 polyphenols and six polyphenol combinations to see how they affected T-cells in the blood.
T cells are a type of white blood cell that circulates throughout our bodies, scanning for cellular abnormalities. Through cell-signaling molecules called cytokines, they call in the troops—other cells—when they find a problem that needs help. Prior to the study, little was known about the relative potency of different polyphenols in modulating cytokine release, according to a University of Liverpool release about the research.
University of Liverpool’s Sian Richardson, a co-author of the study, said: “The results of our study suggest that (poly)phenols derived from onions, turmeric, red grapes, green tea and açai berries may help reduce the release of pro-inflammatory mediators in people at risk of chronic inflammation. Older people are more susceptible to chronic inflammation and as such they may benefit from supplementing their diets with isorhamnetin, resveratrol, curcumin and vanillic acid or with food sources that yield these bioactive molecules.”
Ian: I agree with everything this study concludes. personally, however, I use I LOVE H2 for its anti inflammatory, antioxidant, anti allergenic, anti apoptotic and cell signalling support properties. All in one effervescent tablet.
The results were published in the British Journal of Nutrition.
Recent research has also suggested that vitamin D may be a part of a powerful strategy to reduce chronic inflammation and the related risk of disease.
In the fitness world, inflammation often gets bad press. It is perceived as an enemy of the body simply because when we are inflamed we’ve usually experienced some form of injuries and chronic pain. It’s certainly true that inflammation can be associated with almost about every major health problem we have in medicine today.
So… when people talk of inflammation that they immediately think of it as the bad guy..
This really isn’t the case.
We actually need a healthy amount of inflammation in the body. Inflammation is evidence of an active response to injury or illness by your immune system. Its function is to remove cellular debris from the site of damage and facilitate repair.
Like everyone, you’ve been injured, so your truth is that the injured area becomes stiff and sore. Your body can’t actually speak, so its way of telling you to be gentle on yourself is to limit range of motion in the affected area to prevent further damage. The body is applying its own version of a “splint” to allow it time to heal. Increased inflammation isn’t bad – it’s a part of your healing process.
It’s important not to upset this process by the body so that it can do the job properly.
Right now there’s quite a debate about the RICE (rest, ice, compression, elevation) method. It’s been around in sports therapy for a long time simply because there have been a tremendous amount of studies that show that chilling an area after injury can help it by slowing up the ‘healing process’. Ice slows blood flow, and also slows down inflammation response.
We end up taking on seemingly ‘logical’ methods that, while look good on paper, aren’t really ideal for what we are trying to accomplish. When we are injured, we need inflammation to do its job to heal that area, assist in getting the area mobile again, increasing blood flow, so that the healing process is sped up. But.. we don’t consult our own body about the strategy, do we? If we did it’d most likely:
Go Away and let me get on with my time-proven healing system!
Inflammation is not ‘bad’. It has many positive benefits. The real issue with inflammation is preventing it becoming chronic. This is when inflammation starts creating problems in our lives.
Much exercise creates what is terms by sports scientists as ‘micro trauma’ at the cellular level. We mortals call it muscular damage.
When this happens there’s a repair process that does involve an inflammatory response. Its purpose is a positive one that we should try to accept. It helps to promote healing and it is a part of the process of helping your muscles get stronger, and more ready for future training sessions. Actually, it’s often a stated goal of training regimens. This is the mild form of inflammation, and many of us feel it after exercise. It’s a component that helps us avoid more soreness from future training sessions. Most of us understand the process. It’s a part of the adaptation principle to stresses or demands on our body. In this way we can see the healthy inflammation response as something we can welcome in order to get stronger, faster, and more prepared for future training sessions.
This is a good thing… but chronic inflammation is something very different.
Chronic inflammation occurs when we managed to cause either too much damage at the cellular level, or we have created repetitive stress in a particular joint or soft tissue. Go crazy in the gym and do four times as much work as you usually do and can’t walk right for days and days after. That’s a good way to get chronic inflammation.
Excessive muscle soreness can seriously compromise our performance – just because we can’t actually stand the pain. One study of runners experiencing severe delayed onset muscle soreness showed running performance was reduced by as much as three percent. It may not look like a lot, but when over the entire lifetime of a runner’s performance lifespan their economy is only reduced on average by about 10 percent, that’s a significant amount.
So.. a bit of soreness isn’t much to worry about. It’s part of our natural adaptation to a new body stressor. However, a significant degree of soreness that changes movement patterns means that the joints will end up moving in ways to protect the injured area and create an environment for more injuries or problems.
Ok. So where does that leave us? For me, at age 69, my running days are over and I can amass enough pain and stiffness from a day in the garden. I have found two things to be very, very helpful, to the point that s long as I remember them, I am up bright and early the next day ready for another round of weed pulling.
I have two golden rules” Drink enough water – obviously my alkaline hydrogen rich water.. and I boost that with a small bottle of the same water plus two I LOVE H2 tablets dissolved in the same water, so I am getting a real ‘hit’ of H2.
And why am I so confident of this strategy? Well it works for me, but if you care to take a closer look at the amazing science of molecular hydrogen you’ll see that just one of its many health supporting properties is support for our natural inflammation cycle. In short, it supercharges my perfectly normal and healthy inflammation response and so shortens the time it takes to do the job I’ve set it with my previous day’s exertions.
More on my water here
More on I LOVE H2 here
All the science here
OK, It’s a war zone ‘down there’. Or at least a ‘postwar zone. Your elimination system has been battling with acid overload all night, and in the early hours of the morning has assembled all that nasty acid in your bladder. That’s why your first ‘pee du jour’ is your most acidic.
It’s obvious that your body has worked selflessly to get you back in balance ready for another day battling the dark acid forces.. so it’s a really good idea to begin a daily practice of supporting your fragile alkaline balance.
It’s something I love.. and I am already a serious ‘alkalizer’.
If you already have a routine — morning meditation, a quick surya namaskar, a brisk walk around the block – I’m suggesting you add this to your ‘package’ of morning ritual. As Anthony Robbins teaches, by linking it to other daily choices, it becomes a part of the whole.
So here’s my suggestion. It’s neither original nor new, but it is GOOD. A glass of warm lemon water with Himalayan salt.
If you take on this daily ritual you’ll be joining many elite athletes who have already learned its value.
One 250ml glass of warm lemon water with Himalayan salt in the morning can do wonders. Would you believe increasing your immune function, decreasing your uric acid to fight inflammation, improving digestion, and balancing your body? Much of this is the vitamin C in the lemon juice plus the many essential minerals in Himalayan salt.
When I began writing this I could think of about 6 benefits. After a little time communing with Mother Google, I ended up with NINETEEN benefits!
1 Lemons are serious anti inflammation warriors.
The juice can help dissolve the uric acid in joints. It’s also have been reported to help build and repair tendons, ligaments, and bone.
Lemon juice’s anti-inflammatory property could of course be especially beneficial for people with rheumatoid arthritis and osteoarthritis, according to an American College of Physicians study on osteoarthritis, published in the Annals of Internal Medicine (2000).
2. Lemon juice supports good food and water absorption.
Only one glass a day will provide a better overall mineral balance, which in turn promotes proper food and water absorption in your body, allowing essential nutrients to get where they need to be.
3. Alkaline Powerhouse! (pH). The alkalizing effects of lemon and the natural salt are going to buffer your body’s delicate pH balance, depositing alkaline minerals into your depleted storehoue, your alkaline buffer.
4. Boost immune function.
Just 1 lemon serves up 139% of your RDA for vitamin C. One lemon’s juice is a natural alternative to that vitamin C supplement you may be taking.
5. Cellular detox
Himalayan salt mixed with lemon juice and water helps to pull toxins from your cells, reducing cellular toxicity. How? Well, your interstitial liquid – the liquid surrounding your cell has to be the right pH because it needs it for the right electrical conductivity. That’s why alkalizing is so important, and also why pure neutral pH is empty in health terms.
6. Bye Bye cellulite.
Natural salts like Himalayan salt have been used for centuries for skin care. Many spa treatments for cellulitis contain some form of salt and/or citrus blend. A daily gulp of lemon and salt water in the morning may firm up a few of those unsightly areas. Now you’ve mastered one, why not two!
7. DayGlo Skin.
Natural salt for skin problems, such as psoriasis and eczema, dates back to ancient Roman times. According to Science Tribune (1999), Roman emperor Marcus Aurelius’ doctor, Galen from Pergamum, used sea salt for skin diseases,
8. Ease up on allergies!
Some people say that the combination of lemon and salt, mixed into warm water, acts as a natural antihistamine for allergies. It may be the perfect alternative to those pink pills that leave you feeling drowsy. I can’t vouch for it but if we are getting all these other benefits, wouldn’t it be cool if it ‘just happened’?
9. Sleep Easy.
Lemon and Himalayan salt have hormone-balancing properties, which may be more than useful at ‘zedtime’.
10. Control blood sugar.
According to a study published in the New England Journal of Medicine (2000), the fiber in lemons helps to balance blood glucose levels, which is useful for type 2 diabetes patients and prediabetics alike, so don’t bother holding back the fibre as you juice.
11. Detoxify your liver.
Vitamin C helps us to produce glutathione, a foundational player in detoxifying the liver. It also has antiseptic properties that are useful for liver function.
12. Fresh breath! This drink may not be the first thing we think of when you think of fresh breath. Lemon and salt in this simple morning drink help kill the bad breath bacteria that build up while you’re sleeping.
13. Chill out!
Easy on the anti depressants! Chill out and return to Buddhahood by upping your vitamin C levels first thing in the morning.
14. Blood pressure.
Lemons are not all about vitamin C and fiber. They also have potassium, which is a must-have for flushing excessive sodium from the body.
15. Hey, Baby!
The same vitamin C content and hormone-balancing properties of our drink can help lift your mood. And a good mood is essential for a more er.. playful future.
16. Hydration is the KEY
We tend to forget how important hydration is, especially after a long sleep with no water. Start your morning off right and get hydrated. The water, salt and lemon will get your day off to the perfect start.
17. An antioxidant powerhouse.
Lemon holds a wealth of vitamins and minerals. Himalayan salt boosts your mineral and trace mineral levels even more. The antioxidant and detoxifying properties of lemon saltwater pack a powerful, free radical knockout punch.
18. Improve your heart health?
Lemons and real salt are reported as exceptional for increasing heart health on their own. Combine the two into one vibrant morning drink, for chest-thumpin’ health..
As I mentioned earlier, natural mineral rich salt supports electrochemical reactions in the body. According to a study published in the American Journal of Clinical Nutrition (2006), the Vitamin C in our lemon zinger is, “associated with lower endothelial dysfunction in men with no history of cardiovascular disease or diabetes,”
19. A Well Belly
Before breakfast, or any meal, this drink will signal your liver to produce the essential bile needed to clean out harmful gut bacteria. The fiber content and natural salt will also promote digestion.
A glass of AlkaWay purified water rich in H2 (what else?) with a squeeze of one lemon plus half a teaspoon of Himalayan salt. Too easy.
More great alkalizing ideas are in our New Alkaline Diet and Defence Program, available here now. It’s approaching 5000 downloads and is packed with 16 years of accumulated wisdom.
And yes, it’s free right now.
Our friend Bert Middleton is the Gout Killer and this is a great post. Look when it was written! He’s still relevant today!
This Is Where It All Begins.
I hate to be the one to tell you but . . . you probably have gout because your gout diet isn’t exactly and anti-inflammatory diet.
But what are you gonna do? Just run right out there and get yourself one? Change your whole life? Give up all the stuff you love?
It’s going to be easier than you think, I promise, and you’re going to love it. There are some great solutions and you’re gonna be damn happy you found them.
Other Than an Anti-inflammatory Diet,
What Are the Alternatives?
Think back to the last time you had an attack. How long ago was it? Do you remember how it started? How long did it last? How did you finally get rid of it? What does it feel like when it starts to come on? Do you recognize it when it first starts to creep in? Do you panic? What DO you do?
The question is: How does “inflammation” happen in the body? What actually happens?
Here’s a brief explanation:
- “Inflammation is the body’s to response to injury or disease. Typically the heat, swelling and redness are due to increased fluids and white blood cells moving into the affected area to fight infection or protect the damage.”
- “The anti-inflammatory response happens on a chemical, cellular and molecular level, either biologically or with the assistance of different drugs and food sources and/or icing.”
(that is about as technical as you are going to see me get)
To get this conversation about an anti-inflammatory diet started, let’s make a note about one thing: Antioxidants.
If you Google “anti-inflammatory diet”, you will get endless search results for antioxidants, polyphenols, and flavonoids.
For the second part of your homework, get back to Google and go down the list of all the diseases and illnesses that are linked to free radical damage and combine them on your search like this: Heart Disease + Inflammation
Go one by one and try them all. What did you find? Did they all have some sort of connection with systemic inflammation? As in when chronic inflammation moves beyond the immediate tissues and on into the lining of the blood vessels and organs.
Here’s the Scary Thing . . .
. . . if you have gout you are also at risk for at least one or more of those diseases on that list.
Are you wondering which food has the most antioxidants in it? And how do you measure how much antioxidants are in a particular food? Keep reading. We briefly touched on what foods and food groups are high in antioxidant content on both my antioxidants page and my flavonoids page.
The Anti-inflammatory Diet Rundown:
- Many fruits have the antioxidant power to help bring down inflammation. A few are blueberries, peaches, oranges, cherries, and apples. Usually the darker the skin the better.
- Vegetables like spinach, broccoli, beets, onions, and squashes are a start. Dark leafy greens are always a good choice.
- You have to be careful with beans and legumes. They are typically big sources of protein and their is an important balance that needs to be maintained when it comes to gout. In moderation red, black, pinto, and kidney beans are known to be a good source of antioxidant potency.
- A few different grains offer some free radical protection but they are not at the forefront of the better choices. Rice, wheat, rye, soybean seeds and wheat bran have a component called Inositol that show some evidence for protection from the ultra-violet radiation from the sun.
- Healthy fats, oils and nuts can be very good for keeping with the anti-inflammatory diet but not always because of their antioxidant content. Salmon and other fatty fishes are good for omega-3 fatty acids and are known for their anti-inflammatory assistance. Pine nuts and pecans are well-known antioxidants and olive oil is often referred to for it’s polyphenols.
- Soy products have a wide range of antioxidant producing activity that should be noted for it’s Isoflavones.
- Various mushrooms like shiitake and oyster mushrooms are not antioxidants but are a good choice for their anti-inflammatory abilities.
- Clean sources of protein like organically grown chicken and grass-fed beef help keep inflammation down as well as omega-3 enriched eggs and raw-milk dairy products. (remember: pesticides, antibiotics and growth-hormones are potential instigators of free radical damage)
- A variety of spices like tumeric, curry, ginger, garlic, cinnamon, basil and others have many anti-inflammatory qualities and some are strong antioxidants.
- Green Tea is always in the news for it’s antioxidant power.
- Supplements are essential but it gets into some fairly technical speak about how vitamins and minerals get absorbed in to your system compared to regular food. The term “functional food” is now commonplace. They can be absorbed and used by the body more easily but still have high value in vitamins, minerals and nutrients. Supplements in general promote a fair amount of antioxidant activity.
But now we are getting to the good ones: red wine and dark chocolate! This is good since you and I have the “Disease of Kings”. Can we cure gout with red wine and chocolate? We would certainly have the most popular “anti-inflammatory diet” out there if we could.
Red wine has been in the news because it contains the antioxidant resveratrol. I’ve experimented heavily with this one to try to understand the proper dosage for ample anti-inflammatory response but I’ve not been able to come to any conclusions.
Dark chocolate or more specifically, raw cacao has also been in the news heavily for its high antioxidant content. Raw cacao has one of the highest, if not the highest ORAC scores of all known food sources.
Food . . . Anti-inflammatory Diet . . . Be Thy medicine” ~ Hippocrates
Ian: Personally, I’ve been getting and hearing great results from our molecular hydrogen water and dissolvable tablets. Molecular hydrogen is an emerging buzz subject that is attracting huge interest – 700+ scientific studies since 2007, over 150+ disease types. The two that have really interested me are it unequalled antioxidant capability and its anti inflammation ability.
The US National Institute of Mental Health says we now have over 40 million Americans affected by a mental or emotional condition. Then there is the other 50 million who suffer from intermittent bouts of anxiety and depression.
Wow. That’s nearly one third of the US population with mental health issues.
Scary? Damn right it is!
NIMH says just over 50% of adults with a serious mental illness get treatment .
This typically includes inpatient care (7.5 %) and outpatient therapy (40.5%), but the ‘top dog’ is prescription drugs (antidepressants and anti-anxiety drugs).
Although people do achieve relief of their symptoms—side effects can be far worse than the original condition.
Think… suicidal thoughts or actions, the development of tics, liver damage, violent, aggressive or homicidal behavior and impaired immune function, to name a few.
What no-one talks about Neurotransmitters
Google how your brain works, and you’ll begin to understand why mental health conditions make a lot more sense…and you can see that there are other (safer) ways to deal with them!
Billions of cells in my brain talk to each other, exchanging information in the form of chemical messengers called neurotransmitters.
If brain cell ‘Fred’ wants to send a message to brain cell ‘Wilma’, Fred releases the proper neurotransmitter. The neurotransmitter floats across a miniscule space between the two cells (the synaptic cleft) and the receiving cell, Wilma, “catches” the message in one or more of its “catcher’s mitts” (neuroreceptors).
And it happens at the speed of light – or at last it should if everything is working to the max.
When the message is delivered, the leftover neurotransmitters need a cleanup. This happens in one of two ways:
- They are broken down by enzymes, pass through the liver and end up in your urine or feces
- They get sucked up by little “vacuums” (reuptake pumps) to be recycled.
The Big Stars of your Neurotransmitter Inner World.
Although your body has over 50 neurotransmitters, you do have an A-Team. Here are the nutrients they are made of: We’ll look at the common and less common ones and what happens if you are short on them.
Function: Regulates your appetite, mood, sensory perception and immune function.
Deficiency: Depression, eating disorders, chronic pain, sleep disorders, emotional problems, anxiety and aggression.
Food: Amino acid tryptophan, B vitamins, vitamin C, zinc and iron.
Gamma amino-butyric acid (GABA)
Function: Calming effect on your mood.
Deficiency:Anxiety, over-excitability, seizure disorders and mania.
The recipe: The amino acid glutamate, vitamin B6, manganese, biotin, lysine and taurine.
Function: Controls your arousal, movement and hormonal responses.
What deficiency can cause: Muscular and cell rigidity, tremors and Parkinson’s disease.
Food: The amino acids tyrosine or phenylalanine, vitamin B6, folic acid, iron, copper, magnesium and zinc.
Function: Controls electrical activity of your brain and is vital for memory storage.
Deficiency: Memory loss, depression, confusion and muscle incoordination.
Food: The amino acid choline, vitamins B6, B5 and B3, manganese, lysine and threonine.
Medications method of ‘helping’ neurotransmitters.
Psychiatric drugs achieve their intended effect by artificially manipulating our neurotransmitter levels.
Some antidepressants block our reuptake pumps from vacuuming up leftover serotonin. The drug forces serotonin to hang around between our brain cells, making us feel “happier.”
This can get nasty. It can eventually cause you to have too much serotonin—which can make your depression even worse!
By encouraging proper levels of neurotransmitters in your body, you could feel a whole lot better from mental health conditions!
Ways you can naturally help support your neurotransmitters…and your state of mind!
- A whole foods diet with lots of organic fresh fruits, green vegetables, grassfed meats, line caught fish, real grassfed butter, coco and olive oil, eggs. These foods that will load us up with the proper nutrients for your body to make your neurotransmitters. We ‘bring home’ our manufacturing process.
- Drop the soda, sugars and refined carbs. These leach essential nutrients from your bodyand are seriously addictive, even causing many mental conditions. If you don’t believe it, stop eating them fopr 2 weeks a see what your bosy and mind make up to force you back onto them!
- Encourage a healthy gut with probiotic supplementation or fermented foods. The majority of your body’s serotonin is created in your gut. From there it is sent express to your brain. Gut health is crucial to brain health!
- Make sure you have enough vitamin B12. B12 supports a process in your body called methylation. Methylation is vital to the formation of many neurotransmitters, and methylation abnormality is a factor behind mental health problems.
- Get sources of Omega-3 essential fatty acids like wild caught fatty fish. Omega-3 EFAs are vital to brain health. Supplement with a purified fish oil formula if your diet is lacking in this area.
- The new kid on the block is molecular Hydrogen. How does Molecular Hydrogen fit into this picture? Let’s look in more detail.
From the 700+ scientific studies so far, one benefit claim clearly emerges: one of the main actions of H2 is to improve cell signalling; in the brain, cell signalling is done by neurotransmitters.
We certainly need the nutrients mentioned above to make neurotransmitters, but it may not be enough. We also need the body to recognise that the neurotransmitter needs to be made. It has to send the message that the nutrients need to be used for that particular purpose. This message delivery is carried via cell signalling, and with our modern lifestyle and constant sate of low to mediam level toxicity, occasionally the body needs help with maintaining optimal cell signalling. H2, it appears, can do this.
A good number of studies have now shown H2 can increase a number of neurotransmitter levels, including dopamine, epinephrine and acetylcholine. In the studies, scientists were able to conclude that increase in dopamine levels were sufficient to lead to a reduction in Parkinson’s symptoms.
In addition to molecular hydrogen’s cell signalling role, it is also anti-inflammatory. This is important to our brain as well as our body. Between the brain and the rest of the body is the blood brain barrier (BBB). This semi-permeable membrane, when functioning optimally, allows the brain’s essential nutrients and neurotransmitters into the brain, and keeps everything else out. However, in less than optimal health, the BBB can become more porous and let things into the brain that are detrimental, such as free-radicals and heavy metals. This increase in porosity can be due to inflammation.
Heavy metals and excess free-radicals in the brain may contribute to the development of neurodegenerative conditions such as Parkinson’s and Alzheimers. They can not only destroy the neurotransmitters. They can damage the receptors. We certainly need sufficient neurotransmitter levels, and proper functioning receptors for proper brain function. By decreasing inflammation at the BBB, molecular hydrogen can help reduce free-radical damage to the neurotransmitters and their receptors.
Molecular Hydrogen is also a selective antioxidant, so it mops up free radicals.
Therefore, in addition to its role in helping neurotransmitters and their receptors talk to each other, and keeping the bad guys out of the brain, it can also help mop up any of the bad guys that do happen to find their way into the brain.
Scientific Studies suggest that Molecular Hydrogen can:
- Help increase the levels of neurotransmitters
- Protect neurotransmitter receptors from damage
- Improve the function of the blood brain barrier
- Reduce free-radical damage in the brain.This video is a discussion between friends about the effects of molecular hydrogen on depression and brain.
For more information on how to access H2, go here.
What single biological function has been essential to every living organism’s growth, health and advancement – and is more important than any other?
It’s called cell signalling; the ability for one cell in the body to ‘talk’ to another.
Now here’s another question for you. What biological process does one in every three pharmaceutical drugs attempt to assist?
Now there’s a link between today and our lifeforms all the way back to ‘slime’.
University of British Columbia researchers have identified a common ancestral gene. This gene’s function – cell signalling – enabled the evolution of advanced life over a billion years ago.
Found in all complex organisms, including plants and animals, it ‘encodes’ for a large group of enzymes known as protein kinases that enable cells to rapidly transfer information from one cell to another.
“If the duplications and subsequent mutations of this gene during evolution didn’t happen, then life would be completely different today,” said Steven Pelech, a professor in Division of Neurology in the UBC Faculty of Medicine. “The most advanced life on our planet would probably still be bacterial slime.”
Plants, animals, mushrooms and more all exist because they are made up of eukaryotic cells that are larger and far more complex than bacteria. Within these eukaryotic cells are hundreds of organelles that perform billions of diverse functions to keep them living, just as different organs do for the human body.
The new research, published this week in the Journal of Biological Chemistry, identified the gene that gave rise to protein kinases. On a cellular scale, these highly interactive signaling proteins play a role similar to the neurons in the brain by transferring information throughout the cell by a process known as protein phosphorylation.
This ability to transmit signals from one part of the cell to another not only enabled cells to become more complex internally, but also allowed cells to come together to form systems, paving the way for the evolution of intelligent life.
Research into these enzymes is obviously very important to medicine. There are more than 400 human diseases like cancer and diabetes linked to problems with cell signaling.
Disease occurs when a cell gets misinformed or confused.
Today about one-third of all pharmaceutical drug development is targeted at protein kinases. For more than 30 years, researchers have known that most protein kinases came from a common ancestor because their genes are so similar.
“From sequencing the genomes of humans, we knew that about 500 genes for different protein kinases all had similar blueprints,” said Pelech. “Our new research revealed that the gene probably originated from bacteria for facilitating the synthesis of proteins and then mutated to acquire completely new functions.”
Cell signalling has another ally which is most unlike any pharmaceutical drug. Molecular hydrogen is the subject of 700 scientific studies, over a 150+ range of disease conditions, and as well as been identified as a potential selective antioxidant, anti-inflammatory and anti-allergenic, it has also been studies for its ability to assist cell signalling.
Why should we care? We have our cupboard full of pills and potions. Why should we try molecular hydrogen?
The secret lies in its nature. H2 – molecular hydrogen is the smallest molecule in the universe, made up of two of the smallest atoms in the universe. This gives it unique properties that place it in a class of its own. Firstly, its size means the once in the body it has the ability to pass through nay part of the body, including bone, muscle, even into the mitochondria within a single cell. Secondly, it is a simple molecule. What it does – it’s shouldn’t do. Pharma giants are shaking their heads in disbelief at the results users are claiming – results normally reserved for expensive and complex formulated drugs. In truth, at this stage of research, no-one knows why it has so many therapeutic effects, but the results are certainly obvious in the studies.
Want to learn more? Check this slide show prepared by Erica Whisson, Alkaway’s inhouse naturopath.
And.. if you’d like to try molecular hydrogen for yourself, here’s two ways.
The UltraStream I LOVE H2
How do you set yourself up for the day? A natural alkaline ‘shot’.
I love to get up early, a bit of yoga, meditation without fail, a shower, a healthy paleo breakfast,and then out the door. Sound familiar?I think my morning routine is already exceptional. But I have a mighty elixir that compliments my regimen fabulously.
Perhaps you’ve read that warm lemon water wets your mojo working in the morning and optimizes your health. You may even drink warm lemon water with Himalayan salt, or warm lemon water with honey in the morning.
But… have you tried warm lemon water with cinnamon, and the most essential ingredient to this morning elixir, turmeric? (Yes, a bit of honey if you must!)
If you haven’t it, this one, you may be missing out on an truly great way to start your day. Lemon and turmeric are very powerful tools that have a wealth of health beneficits.
Lemons have that tasty, tart flavor with so many health-promoting properties. A study published in the Chemistry Central Journal (2015), says lemons possess a treasure trove of natural metabolites.
Listen to this:
“Citrus fruits exhibit plentiful bioactivities including antioxidant, anti-inflammatory, anti-cancer, antimicrobial and anti-allergy activities, as well as cardiovascular effect, neuroprotective effect, hepatoprotective effect, obesity control, etc.”
But wait for it:
Couple lemon with turmeric, and your health and wellness benefits increase almost exponentially!
Turmeric (Curcuma longa) is a yellow-orange spice that is part of the ginger family. Native to tropical South Asia, turmeric is well known in traditional Asian medicine and cuisine.
More recently, its health benefits have been recognized in Western medicine. According to a study published in theJournal of Nephropathology (2012), “Turmeric, a neglected Asian traditional drug might reemerge as remedy and/or preventive tool for various illnesses including different type of cancers, obesity, type-2 diabetes, hyperlipidemia, hypertension, CKD [chronic kidney disease] and ESRD [end stage renal disease], which are steadily increasing globally, claiming many lives and tremendous amount of resources worldwide.”
Just one of a number of active ingredient in turmeric, curcumin, has been the focus of several academic studies.
Curcumin may alleviate inflammation:
According to research from the Department of Stomatology at the University of California, San Francisco, curcumin possesses anti-inflammatory properties. The research, published in the Journal of Alternative and Complementary Medicine(2004), found that curcumin, “may exert its anti-inflammatory activity by inhibition of a number of different molecules that play a role in inflammation.”
Curcumin’s anticancer potential:
Curcumin may play a vital role in cancer prevention, according to a study published in BioMed Research International (2014). Previous research has highlighted curcumin’s antioxidant, antibacterial and antitumor properties, according to the study, which concluded, “Curcumin, a vital constituent of the spice turmeric, is an alternative approach in the prevention of cancer.”
Therapeutic applications of curcumin:
According to a review study published in the AAPS Journal (2013), “curcumin has shown therapeutic potential against a number of human diseases,”including multiple types of cancer, inflammatory bowel disease, irritable bowel syndrome, arthritis, peptic ulcers, psoriasis, H. pylori infection, Alzheimer’s disease, acute coronary syndrome, atherosclerosis, diabetes, and respiratory tract infections.
So.. here’s my secret morning elixir.
What you’ll need…
1/2 a lemon, squeezed for juice
1/4 – 1/2 tsp turmeric
1/2 tsp honey if you can’t take it!
1/4 tsp cinnamon powder
1 cup warm water.
How to make it…
Mix the lemon juice, turmeric and honey into your cup of warm water. Stir well. Sprinkle cinnamon on top and continue to stir your morning elixir as you drink it (this will ensure that the turmeric doesn’t settle at the bottom of your cup.
Turmeric with its main active ingredient, curcumin, may be that one healthy addition to your morning routine you’ve been looking for. I enjoy this elixir nearly every morning with fruit, which adds a sweet, delicious twist.
And to all my alkalizing friends.. you are setting yourself up with the best alkalizing juice in the world. Just go easy on the honey, honey!
Scientists have discovered a new way information may be traveling throughout the brain. The team has identified slow-moving brainwaves it says could be carried only by the brain’s gentle electrical field, a mechanism previously thought to be incapable of spreading neural signals altogether. (I’ll tell you why I think this is important at the end of this article.)
Dominique Durand, professor of biomedical engineering at Case Western Reserve University says “Researchers have thought that the brain’s endogenous electrical fields are too weak to propagate wave transmission, But it appears the brain may be using the fields to communicate without synaptic transmissions, gap junctions or diffusion.”
What led Durand and her team of researchers to this conclusion was the recording of neural spikes traveling too slowly to be carried by conventional means, indicating something else was at play. They claim that the only possible explanation for the passage of information in this way was the presence of a weak electrical field.
The team tested its theory both by way of computer modeling and observing activity in the hippocampus of a mouse brain, the central region associated with memory and spatial navigation. While the electrical field was weak, with an amplitude of around 2.6 mV/mm, the team found that beginning with one cell or a group of cells, the field was able to stimulate neighboring neurons which in turn stimulated their neighboring neurons. This resulted in a spread of signals throughout the brain at a rate of around 10 cm per second.
By blocking the electrical field and increasing the distance between the cells in the computer model, the team found they could slow down the speed of the wave. This furthered their belief that the mild electrical field is in fact behind the propagation of these type of brain signals.
“Others have been working on this phenomena for decades, but no one has ever made these connections,” says Steven J. Schiff, director of the Center for Neural Engineering at Penn State University, who was not involved in the study. “The implications are that such directed fields can be used to modulate both pathological activities, such as seizures, and to interact with cognitive rhythms that help regulate a variety of processes in the brain.”
The research team says that the newly unearthed mechanism could be behind the spread of neural signals such as sleep and theta waves (those associated with memory formation during sleep), along with epileptic seizure waves, all of which travel at around 1 m per second. They are now exploring what part, if any, they play in epilepsy and regular brain function. If a role is established, they will seek to uncover what information the fields are carrying and where exactly they begin.
The research was published in The Journal of Neuroscience.
Ian: I have become very interested in cell signalling since I realised that perhaps the most valuable benefit of molecular hydrogen is in its ability to support cell signalling. For those of us not yet aware, cell signalling is what happens millions of times a minute in the supercomputer we call the body. It’s the process where one element of the body wants to ‘tell’ another part of the body something, e.g. ‘Move my left leg’. Contemplating this will soon lead you to a realisation of the massive number of messages our body processes along with the infinite complexity of organising this process of cell signalling.
I recently turned 69 and I drink my Ultrastream hydrogen infused water every day, but to ‘up’ the H2 concentration, I first pour it from my UltraStream into a 350ml bottle, to the top, ad 2 x I LOVE H2 tablets that dissolve and release more hydrogen, so I have what some may call a ‘megadose’ of infused H2. I know from study and experience that the higher the concentration of H2 in my water, the more effect it has on my body.
How do I feel? Sharp as a tack. I work hard here at the AlkaWay office every day, and I do attribute that (at my age) to the effect molecular hydrogen has on my internal super computer.
INFLAMMATION: IT’S A “HOT” TOPIC.
It seems connected to avirtually every known chronic disease — from diabetes to obesity, heart disease to cancer, autism to dementia… even depression.
Inflammatory diseases such as allergies, asthma, arthritis, and autoimmune disease are also increasing at dramatic rates. Doctors are trained to shut off inflammation with aspirin, anti-inflammatory medication such as Advil or Motrin, steroids, and increasingly powerful immune suppressing medication with the usual associated side effects.
Doctors are really not trained to find and treat the underlying causes of inflammation in chronic disease. Hidden allergens, infections, environmental toxins, an inflammatory diet, and stress are the real causes of these inflammatory conditions, but that’s a big ‘ask’ for a 15 minute standard consultation.
Let’s look at one ‘niche’ of inflammation. Autoimmune diseases now affect 24 million people. They include rheumatoid arthritis, lupus, multiple sclerosis, thyroid disease, inflammatory bowel disease, and more. And yet.. these are often addressed using powerful immune suppressing medication and not by addressing the cause. A bit like taking a lot of aspirin while you are standing on a tack. The treatment isn’t more aspirin or a strong immune suppressant. It’s removing the tack.
Inflammation Causes Disease
To cool off inflammation in the body, first we must find the source. Functional medicine, the emerging 21st century paradigm of systems medicine, teaches us to treat the cause, not only the symptoms, to ask the question WHY are you sick, not only WHAT disease do you have.
Autoimmunity: What it is and How it Occurs
We are facing an epidemic of allergic (60 million people), asthmatic (30 million people), and autoimmune disorders (24 million people). As we already said, autoimmune diseases include rheumatoid arthritis, lupus, multiple sclerosis, psoriasis,celiac disease, thyroid disease, and the many other hard-to-classify syndromes in the 21st century.
These are all autoimmune conditions, and at their root they are connected by one central biochemical process: A runaway immune response also known as systemic inflammation that results in your body attacking its own tissues. Your immune system is your defense against invaders. It’s your internal army and has to clearly distinguish friend from foe — to know you from others. Autoimmunity occurs when your immune system gets confused and your own tissues get caught in friendly cross-fire.
Your body is fighting something — an infection, a toxin, an allergen, a food or the stress response — and somehow it redirects its hostile attack on your joints, your brain, your thyroid, your gut, your skin, or sometimes your whole body.
This immune confusion results from what is referred to as molecular mimicry. Conventional approaches don’t have a method for finding the insult causing the problem. Functional medicine provides a map to find out which molecule the cells are mimicking.
Where Do Autoimmune Disorders Happen?
Interestingly, autoimmune disorders occur almost exclusively in developed countries. People in poor nations without modern amenities like running water, flush toilets, washing machines, and sterile backyards just don’t get these diseases.
If you were a farm kid with lots of animals, you are also less likely to have any of these inflammatory disorders. Playing in the dirt, getting dirty, and being exposed to bugs and infections trains your immune system to recognize what is foreign and what is “you.”
In this country, autoimmune diseases, when taken all together, are a huge health burden. They are the eighth leading cause of death among women, shortening the average patient’s lifespan by eight years. The annual health care cost for autoimmune diseases is $120 billion a year representing nearly twice the economic health care burden of cancer (about $ 70 billion a year). (i)
Unfortunately, many of the conventional treatments available can make you feel worse. Anti-inflammatory drugs like Advil, steroids, immune suppressants like methotrexate, and the new TNF-alpha blockers like Enbrel or Remicade can lead to intestinal bleeding, kidney failure, depression, psychosis, osteoporosis, muscle loss, and diabetes, not to mention overwhelming infection and cancer.
When used selectively these drugs can help people get their lives back. But they are really not a long-term solution. They shouldn’t be the end of treatment, just a bridge to cool off inflammation while we treat the root cause of the disease.
9 Steps to Overcoming Autoimmune Disease
- Check for hidden infections — yeast, viruses, bacteria, Lyme, etc. — with the help of a doctor, and treat them.
- Check for hidden food allergens with IgG food testing or just try The UltraSimple Diet, which is designed to eliminate most food allergens.
- Get tested for celiac disease, which is a blood test that any doctor can do.
- Get checked for heavy metal toxicity. Mercury and other metals can cause autoimmunity.
- Fix your gut. For details, see my blog on irritable bowel syndrome.
- Use nutrients such as fish oil, vitamin C, vitamin D, and probiotics to help calm your immune response naturally.
- Exercise steadily regularly — it’s a natural anti-inflammatory.
- Practice deep relaxation like yoga, deep breathing, biofeedback, or massage. Stress worsens the immune response.
- Look at your inflammation habits in your food and water. Alkalize and get a regular supply of infused hydrogen water.
The answers may be right in front of you.
Treat the underlying causes of your illness and you will begin to experience vibrant health once more.
(i) Nakazawa, D. (2008). The Autoimmune Epidemic. Simon & Schuster. New York.
(ii) Siegel, C.A., Marden, S.M., Persing, S.M., et al. (2009). Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn’s disease: a meta-analysis. Clin Gastroenterol Hepatol. 7(8): 874-81.
This is designed for educational purposes only and is not engaged in rendering medical advice, legal advice or professional services. If you feel that you have a medical problem, you should seek the advice of your Physician or health care Practitioner.
For years now I’ve had a piece of ‘knowledge in my head that has made me prey to all sorts of woo woo cures.
It’s the idea that our telomeres in our DNA ‘shorten’ as we get older, and that this is the reason for ageing and decline. The ‘woo-woo’ cures were always using some new ‘technology’ or ‘technique’ either from Russia or Tibet that claimed to use quantum physics to restore telomere health. Of course it’s a complete load of BS but I always looked at the adverts because fixed in my mind was a picture of my trillions of little telomeres randomly dropping bits off their strings.
So today’s news is very good news to me. The big news is that there is a reason that bits drop off them and that reason is something I personally can address. You see, news from a team of experts from Newcastle University’s Institute for Ageing and Keio University School of Medicine, Tokyo is that INFLAMMATION is the cause of telomere destruction.
Why is that making me happy?
Because molecular hydrogen – the same H2 that our UltraStream adds to its pure water oputput, and according to published scientific studies, it’s a super efficient inflammation fighter. We are getting some great reports from users already (see our testimonials page).
In tablet form it’s classified as a sports supplement and Steve, our inhouse trainer swears by it. he plays two games of soccer each weekend and at age 45, he says he was never able to achieve this so easily.
There are some many books, studies and reports on the problem of inflammation. It’s already been linked as a precursor to many of our 5 star diseases – the ones that keep the Big Pharma industry so happy. It’s acknowledged as the big cause that no-one really takes much notice of, but just think; if the scientists are right, then H2 is the fabled ‘elixir of youth’.
The research is in… and it’s saying that many cases of depression are actually caused by an allergic reaction to inflammation.
In NOVA mag, Tim de Chant wrote:
“Inflammation is our immune system’s natural response (my underlining) to injuries, infections, or foreign compounds. When triggered, the body pumps various cells and proteins to the site through the blood stream, including cytokines, a class of proteins that facilitate intercellular communication. It also happens that people suffering from depression are loaded with cytokines.”
Inflammation is caused by (among other things like walking into a glass door) obesity, high sugar diets, high quantities of trans fats, and unhealthy diets in general.
Researchers and doctors are opening up an exciting new dimension in the fight against what has become a global epidemic. By treating the inflammatory symptoms of depression — instead of the neurological ones.
The Guardian writes:
“The good news is that the few clinical trials done so far have found that adding anti-inflammatory medicines to antidepressants not only improves symptoms, but also increases the proportion of people who respond to treatment. There is also some evidence that omega 3 and curcumin, an extract of the spice turmeric, might have similar effects. Both are available over the counter and might be worth a try, although as an add-on to any prescribed treatment – there’s definitely not enough evidence to use them as a replacement.”
Eleanor Morgan of VICE adds: “Cytokines skyrocket during depressive episodes and, in those with bipolar disorder, halt in remission. The fact that ‘normal,’ healthy people can become temporarily anxious or depressed after receiving an inflammatory vaccine — like typhoid — lends further credence to the theory. There are even those who think we should re-brand depression altogether as an infectious disease … Carmine Pariante, a Kings College psychiatrist who is quoted in The Guardian report, says that we’re between five and ten years away from a blood test that can measure levels of inflammation in depressed people. If both Pariante’s estimate and the inflammation-depression theory are correct, we could potentially be just five years from an adequate ‘cure’ for depression.”
Ian: Well, well, again and again we are hearing about the anti inflammation power of curcurmin. And we know why. Cucurmin generates H2 in the body. Are we dosing up on curcurmin? No. We are talking H2 tablets in water. Easier, faster, better.
Almost everybody who starts our New Alkaline diet has to deal with cravings. I’m sure even Elle McPherson went through them.
Unless you never ate sugar in your life, you’ve had cravings. Yet… knowing that it’s a common problem doesn’t make it any easier for you.
We’ve found that these tactics help a lot. We are asking a lot to give up your ‘crutch’ your ‘Mother’s Little Helper’ so the least we can do is show you what we have learned about overcoming cravings.
There are a few tactics we have found that work for almost everybody.
5 Crave Stopping Hacks
1. Sleep Enough.
It sounds like an odd first hack, but short on zeds does make you crave junk food. It’s also a sure way to make sure that you don’t have enough willpower to resist because you feel like well… crap..
Without sufficient sleep, 2 things happen.
a) You overproduce cortisol. This makes you hungrier, particularly for sugar.
b) Your body sends less glucose to your prefrontal cortex , your impulse-control center. You have less control over your actions (and your cravings).
How important is sleep? Try living without it.
2. Eat Enough Healthy Fats.
We usually crave non-NAD (New Alkaline Diet) foods because we’re just not eating enough, especially when first starting on the diet. Remember that you’re cutting out a lot of the nasty starches and sugars, so you need a replacement. The health-friendliest and most satisfying way to replace it is with good fats, such as coconut oil, pastured beef fat, avocado fat etc.
Make sure that you eat enough food at every meal. If this doesn’t seem a problem,Sounds like it shouldn’t be a problem, but when you’re changing diet, you often under eat without even knowing.
3. Avoid Snacking.
If you are already a snacker you’ve trained your body like a puppy to beg for food at regular hours. Continue to snack regularly, and you’ll continue to be reminded snack at those times because your body will expect it.
I know, I know. You don’t like this suggestion. just remember the AA maxim. One day at a time.
Once you say no to snackaddiction (and begin eating only nutritious NAD foods), your hunger pangs will cease because you’re getting off the up-down mood cycle so evident in over-acidic people.
4. Drink More Water: alkaline hydrogen rich pure water if possible..
Drinking has the same problems as eating. Being dehydrated supercharges your cravings. You don’t need to drink gallons, but definitely make sure you drink water regularly.
5. Go Cold Turkey.
There’s no easy way to say this. Just do it. We admit we were powerless over alcohol – that our lives had become unmanageable. Face it, Kiddo. If you could have changed your diet, YOU WOULD HAVE! Sugar is by far the most addictive part of non-NAD foods. It isn’t easy to give up processed sugar cold turkey, but if you can do it, your cravings will be much easier to control sooner rather than later. I can absolutely say that my whole food preferences, servings size and enjoyment have all changed as I gave up on sugar (and grains and acidic foods!)
Are you in? Or are you still trying to manage the addict?
PS: Hey, if this resonates with you… we KNOW where you are!
If you want help – really want help – we’ll send our New Alkaline Diet E-Book (150 pages of 15 years of research and hard earned experience)AND add you into the queue for our online program.
Go here to get it free now. We are about to put a price tag on it and convert it to kindle so don’t muck about.
European Food Safety Authority:
Hmm… seems they haven’t read their own name lately!
The European Food Safety Authority (EFSA) has published a new report: ‘The 2013 European Union report on pesticides in food’.
The report, shows the results for almost 81,000 food samples from 27 EU Member States, Iceland and Norway”.
Their Press Release of 12th March 2015 reports that:
“a combined total of 80,967 samples of a wide variety of processed and unprocessed food products were tested for the presence of 685 pesticides”.
It continues, “97.4% of the samples analysed fell within legal limits” but adds that,
“Residues of more than one pesticide (multiple residues) were found in 27.3% of samples”.
That’s one in four!!!! Muliple health and environmental NGOs say that EFSA does not examine the ‘cocktail effect’ of these residues on humans. Martin Dermine of Pesticide Action Network told Euractive,
“Providing statistics of single residue level in food is too simplistic”.
Ian: I totally agree. I cannot understand why people don’t understand that if we are ingesting toxins at this rate we don’t have a plan in place to continually detox – even something as basic as good hydration!
Polybrominated diphenyl ethers (PBDEs) – another totally scary chemical term – seems to be something the bald eagle likes to consume. recently a study of Michigan’s bald eagle population discovered that they are the most contaminated birds on the planet. Banned flame retardant chemicals were found in their livers.The population of bald eagles in the region is stable, but the PBDE compounds have shown, in other birds, to impair reproduction, development, disrupt hormones, and even cause weird behavior.
I guess the most iconic animal in the United States won’t catch on fire too easily…
Originally, companies started putting PBDEs into furniture cushions, electronics and clothing in an effort to slow the spread of flames if they catch fire. Chemicals quickly built up in people and the earth. Despite a phase-out beginning in the early 2000s, PBDEs are still persistent. They are still found in the air, the dirt and yes, everyone on the planet.
The eagles were probably exposed to chemicals that ended up in water, and then in the fish that they eat. Because they are at the top of the food chain, they naturally tend to accumulate higher concentrations than living things lower down. This also makes them early warning indicators for these types of pollutants.
And who else is at the top of the food chain? That’s right, you and me.
Environmental Health News says: “PBDE concentrations were “among the highest found in liver tissues of any wildlife,” the authors wrote, with one eagle measuring 1,538 parts per billion PBDEs in its liver. Americans have some of the highest levels of PBDEs in their bodies worldwide, with studies of U.S. breast milk finding median PBDE concentrations of about 30 ppb, though the types of PBDEs vary.”
Ian: So.. what can we do when we are already contaminated? For me, I love my life so I’m committed to eating good clean food and as many detoxifying greens as possible. I eat meat to get the widest range of amino acids and I drink high H2 water and use high H2 supplements.
Yes, Warren Buffet defies all dietary advice and eats like a 6 year old. Dang, it makes me mad!
Ok..For all other people on earth.. here’s a link to our Free New Alkaline Program. Downloaded by over 1000 people, fully updated. It’s only 7 days and you’ll start feeling the benefits. You’ll probably feel better than Warren Buffet too!
Posted by Dr. Ben Kim
If your immune system falters and begins to identify some of your own tissues as being harmful or unnecessary, it will work to attack and eliminate these tissues through an inflammatory response that can cause pain and discomfort in many forms – this is how autoimmune illness develops.
Your genetics determine the specific tissue or groups of tissues (organs) that your immune system decides to attack.
But just because you have a genetic predisposition for an autoimmune illness does not mean that you are guaranteed to experience it sometime during your life, or that you cannot recover from it.
Genetic predispositions are largely triggered, maintained, and kept under control by environmental factors, namely, your diet, lifestyle, and how much stress you experience.
Ultimately, the development of autoimmune illness requires that your immune system begins to identify some of your own cells as being harmful, and that control mechanisms that are in place to prevent such “glitches” no longer do what they are supposed to in preventing such occurrences.
Several theories that attempt to explain why and how these glitches occur. Rather than get into biochemical jargon that will not do much, if anything, to help you get better, we can explain these glitches in the following way:
Over time, as your cells suffer lack of rest, lack of optimal nourishment, accumulation of waste products, and direct insult by excessive amounts of free radicals and toxins, your cells gradually become less efficient at eliminating waste products and exogenous toxins (toxins that are produced outside of your body).
Eventually, waste products and toxins may incorporate themselves into your cell membranes, and if this happens, your immune system may identify such cells as being old and damaged. At that point, your immune system will work to attack and eliminate such cells from your body.
How does your immune system go about attacking and eliminating such cells? By producing antibodies, attaching said antibodies to the cell membranes of cells that have been identified as old and damaged, and then sending other components of your immune system to destroy these antibody-tagged cells. Your immune system destroys such cells using a process of inflammation, which is why autoimmune illness is often accompanied by discomfort.
If your genetic predisposition is such that the majority of cells that are tagged to be destroyed are clustered around your thyroid gland, your health challenges may be attributed to a diagnosis of Graves’ disease. If your abnormal-looking cells are in the fatty, insulating sheath (myelin) that surrounds your nervous system, you may exhibit symptoms of multiple sclerosis. If your genetically weak tissues are those that line your joints, destruction of old and damaged cells in and around your joints may be diagnosed as rheumatoid arthritis.
Ultimately, the underlying inflammatory process that accompanies autoimmune disease is the same for all of the following names that we have created for different groups of symptoms:
Acute disseminated encephalomyelitis (ADEM) involves inflammation in the brain that typically occurs a few days or weeks after a vaccination or a viral infection.
Addison’s disease involves dysfunction of the outer portion of the adrenal gland.
Ankylosing spondylitis is a type of arthritis that involves inflammation of the spine and pelvic joints.
Antiphospholipid antibody syndrome (APS) is a condition that affects the blood-clotting process, causing blood clots to form in veins and/or arteries.
Aplastic anemia is a condition whereby the bone marrow does not produce enough blood cells. It is often caused by an autoimmune attack on the bone marrow.
Autoimmune hepatitis involves inflammation of the liver.
Celiac disease is characterized by chronic inflammation of the first third or half of the small intestine, and is caused by exposure to a type of dietary protein called gluten, found in abundance in grains like wheat, oats, barley, and rye.
Crohn’s disease involves chronic inflammation of the intestinal tract.
Diabetes Mellitus Type 1 is characterized by low or non-existent production of insulin by the pancreas.
Goodpasture’s syndrome involves destruction of kidney tissue and bleeding in the lungs.
Graves’ disease is a form of hyperthyroidism.
Guillain-Barré syndrome (GBS) involves inflammation of the peripheral nervous system, and is also called acute inflammatory demyelinating polyneuropathy, acute idiopathic polyradiculoneuritis, acute idiopathic polyneuritis and Landry’s ascending paralysis.
Hashimoto’s disease is a form of hypothyroidism.
Idiopathic thrombocytopenic purpura is characterized by a low platelet count, resulting in easy bleeding.
Systemic lupus erythematosus (SLE) is a chronic autoimmune condition that can involve inflammation in the following areas: skin, joints, heart, lungs, kidneys, and nervous system.
Multiple sclerosis involves nerve dysfunction due to demyelination of the central nervous system.
Myasthenia gravis involves intermittent weakness and fatigue due to a problem with communication at the junction of nerves and muscles.
Optic neuritis involves inflammation of the nerves that supply your eyes which can cause partial or complete loss of vision.
Pemphigus is characterized by the formation of blisters and raw sores on mucous membranes and skin.
Pernicious Anemia is a form of anemia (inadequate red blood supply/function) that is caused by a problem with absorbing vitamin B12, which is needed to form healthy red blood cells.
Rheumatoid arthritis is characterized by joint pain and inflammation.
Sjögren’s syndrome involves destruction of glands that produce saliva and tears.
Takayasu’s arteritis is characterized by inflammation that narrows the lumen of arteries.
Temporal arteritis is characterized by inflammation in medium to large-sized arteries, mostly commonly in the head. It is sometimes called giant cell arteritis, and can lead to significant vision loss.
Warm autoimmune hemolytic anemia is characterized by destruction of red blood cells by IgM antibodies.
Wegener’s granulomatosis involves inflammation of blood vessels, typically affecting the kidneys and lungs.
Diagnoses that are not universally accepted as being autoimmune in nature, but for all practical purposes belong in the same category of health conditions, include:
Alopecia is characterized by hair loss. Loss of random patches is called alopecia areata, while full body loss of hair is called alopecia universalis.
Endometriosis is characterized by endometrial tissue (tissue found in the uterus) being deposited outside of the uterus, causing pain and sometimes infertility.
Interstitial cystitis is a urinary bladder disease that is characterized by one or more of the following symptoms: intense, intermittent pelvic pain, frequent urination, a sense of urgency to urinate, pain with urination, and pain with sexual intercourse.
Psoriasis is a skin condition that is characterized by patches of rapidly-dividing cells that produce itchy, scaly, and inflamed lesions.
Sarcoidosis is characterized by granuloma formation in the lungs and sometimes throughout the body.
Schizophrenia is characterized by impairments in the perception or expression of reality, often leading to social and occupational dysfunction.
Scleroderma is characterized by excessive deposits of collagen throughout the body.
Ulcerative colitis is characterized by inflammation in the bowel, typically in the distal section of the large bowel and rectum.
Vitiligo is characterized by gradual loss of pigmentation in patches across the face and/or body.
All of these conditions may be caused, in part, by cells in the problematic regions becoming old, damaged, and congested enough to be tagged by your immune system as being ready for destruction and removal.
But there is another major mechanism by which all autoimmune illnesses can develop and worsen. Whenever any unnecessary, harmful, or unidentifiable substances enter your bloodstream, they get noticed by your immune system. In an effort to preserve your health, your immune system produces antibodies that seek out and attach themselves to these unwanted substances; these substances are generally referred to as antigens.
Once your antibodies attach themselves to antigens, antigen-antibody complexes are formed. Your immune system will work to eliminate these antigen-antibody complexes from your body so that the foreign antigens cannot harm your cells. But if enough of these complexes are formed, your immune system may not be able to eliminate them as quickly as they are formed. This can lead to some of these complexes getting deposited into different tissues, where they can cause inflammation and damage. Typically, the sites at which these complexes get deposited are determined by your genetic predisposition.
Causes of Antigen-Antibody Complex
Formation and Ensuing Inflammation
Perhaps the most common cause of excessive formation of antigen-antibody complexes is having an unhealthy digestive tract.
From your mouth to your anus, your digestive tract is one long tube that is meant to extract nutrients out of your food and allow these nutrients to slip through into your bloodstream so that they can nourish your cells. While your digestive tract is designed for proper digestion and assimilation of nutrients, it is also designed to protect your blood and inner cells against undesirable substances that can become antigens that lead to antigen-antibody complex formation in your blood.
If you abuse your digestive tract long enough with poor dietary and lifestyle choices, it can begin to lose its ability to prevent harmful substances from entering your blood. The lining of your digestive tract can begin to break down, and the population of microorganisms that line your digestive tract can shift from being predominately health-promoting and protective bacteria to largely microorganisms that can break down your digestive tract lining, such as yeast, bad bacteria, and even parasites.
This state – where your digestive tract lining loses its ability to keep harmful substances out of your blood – is often called “leaky gut syndrome.”
Leaky gut syndrome can cause incompletely digested food to enter your bloodstream. And the most problematic incompletely digested food group in autoimmune illness is protein.
Your body expects to receive amino acids – the smaller constituents of protein – into its blood supply, not bigger molecules of protein (several amino acids linked to one another). So when incompletely digested protein enters your blood supply through an unhealthy digestive tract lining, your immune system identifies these molecules as being foreign and potentially harmful. Your immune system will quickly move to create antibodies that can attach onto chains of incompletely digested protein, forming antigen-antibody complexes. And you know what happens next. While your immune system will do its best to eliminate these complexes from your body, if enough of them form because you continue to have a dysfunctional digestive tract and you continue to eat large amounts of protein, some of these complexes will get caught up in various tissues in your body, leading to inflammation and pain.
Incompletely digested protein is not the sole group of substances that can contribute to autoimmune illness in this fashion. Any substances that your body cannot use for nourishment can potentially trigger the production of antigen-antibody complexes and ensuing inflammation. This is why it is important to be aware of common household and environmental toxins, and to do your best to decrease your exposure to them.
For example, great care should be taken to avoid unnecessary exposure to conventional cosmetic products. Lipstick, lip balm, and other products that are typically used around large pores have a relatively easy pathway to your blood supply. It is a well established fact that women suffer from autoimmune illness at a significantly higher rate than men; I have come to believe that this is, in part, due to the widespread use of cosmetics among women – this is a connection that has not been established in the medical literature, it is a personal hypothesis based on my own clinical experiences.
At this point, I hope that it is clear that autoimmune illness, no matter which specific one you are concerned about, is not a local problem in your body; it is a systemic problem that has multiple causes and should be addressed as such.
Put another way, if you want to maximize your chances of experiencing a full recovery and being free of autoimmune illness for the long-term, you must take care of every aspect of your health on a daily basis.
Ian: We have a lovely lady client. Merilyn has RA and has used our products for many years, claiming some relief.. but it’s a nasty ailment and often gets worse rather than better. We are VERY hopeful of feedback from people with inflammation-related disease with our hydrogen products. That’s not a claim: it’s a hope!
We spent a very wet weekend at home here in Byron Bay at the edge of a cyclone. I decided that wet was just a state of mind and stoked up with a BIG energy boost. I had a dose of Rocket Fuel, colloidal minerals and I LOVE H2, donned shorts and tee, and went out to our HUGE pile of mulch that is waiting to be barrowed around the garden. Well, I did around 30 barrowloads in the rain.
Kinda proud of my 69-yearold self, but I do have to give some attribution to my ‘energy cocktail’!
While I was out and about in the garden I couldn’t help but notice how may flowers took the rainy weather as an opportunity to ‘come out’.
Molecular Hydrogen (H2) has already been studied in depth and found to be an antioxidant and an anti-inflammatory. But what about diabetes and obesity?
The development of type 2 diabetes is linked to increased oxidative stress (free radical damage). A study using diabetic mice found that giving them H2 water improved obesity and diabetes parameters.
Scientists divided mice into two groups; one that received hydrogen rich water, and one group that didn’t. The mice were allowed to eat and drink as much food and water as they wanted.
Ah, what a life!
Long term drinking of hydrogen rich water, which for these mice meant 3 months, controlled fat and body weights, and it also alleviated fatty liver. (Fatty liver, if left untreated, can develop into cirrhosis of the liver or liver cancer). There was also an improvement in the levels of blood sugar, insulin and triglycerides; three of the big ones when it comes to the development of metabolic syndrome, Type 2 Diabetes and Heart Disease. The study also found that H2 accumulates in liver glycogen and there was an increase in the levels of FGF21, a liver hormone the enhances use of fatty acids and glucose..
The organs and muscles of the body use glucose as fuel. Carbohydrates, protein and fats need to be converted to glucose to be used. Glycogen is the form in which glucose is stored in both muscles and the liver. From the liver, glycogen can be released to be used as energy by organs and muscles in the body when required. H2 accumulates in liver glycogen stores after being consumed via Hydrogen Rich Water. This means that H2 is available to be used as an antioxidant and anti-inflammatory when required by the body.
As liver glycogen is the form in which glucose is stored for use by every organ and muscle in the body when required, when glucose is needed by any part of the body, that organ or muscle is also receiving H2. So therefore the body’s antioxidant mechanisms are improved and this decreases the free radical damage to the body. As free radical damage is one of the main contributing factors to the development of diabetes it is thought that this increase in antioxidant functions in the body can impede the development of diabetes. The mice receiving H2 water had lover levels of the molecules that indicate free radical damage; in fact the H2 mice had levels of these molecules that were almost the same as non-diabetic mice.
For weight watchers in general, here’s the big one.
The group of mice drinking hydrogen rich water had less body fat than those drinking normal water. Scientists suggest that this reduction in weight gain is because H2 stimulates energy production and the increase in energy produced means less is stored as fat.
One of the mechanisms they found for this was an increase in the hormone FGF21, which is a hormone released from the liver that enhances the use of fatty acids and glucose for fuel and results in improved insulin sensitivity and glucose clearance. This indicates not only increased energy production and lower fat storage, but also lower levels of blood glucose and triglyceride levels.
To measure energy consumption scientists measure the oxygen an animal inhales and the carbon dioxide it exhales. The difference between the two shows how much energy is being produced. The mice on the Hydrogen rich water produced more energy than the normal water mice; this was with no discernable increase in movement.
For diabetics there is also good news. In diabetic mice, the consumption of Hydrogen Rich Water improved diabetic parameters. We need to be careful in extrapolating from animal studies to humans. However, there have now been numerous human studies showing that H2 can reduce oxidative stress and blood parameters in patients with diabetes. The theory is that drinking hydrogen rich water improves blood parameters and body weight in diabetics and people with insulin resistance by increasing FGF21 and energy consumption. Of course, it warrants further investigation – but if it is true…
Hydrogen rich water can be accessed by a number of methods. An electronic water ionizer will deliver low levels of H2 with the water using electrolysis. A natural water ionizer will deliver up to 4 times the amount at far less cost. A new tablet will deliver even more by dissolving in water. Stay tuned.
- Hepatic FGF21: Fibroblast Growth Factor 21 (FGF21) A liver hormone the enhances use of fatty acids and glucose.
- Energy Metabolism: The conversion of nutrients into fuel to be used by the body.
- db/db Mice: Mice with diabetes.
- Liver glycogen: Form in which glucose is stored in the liver. It can then be released into the blood stream to supply muscles and organs with energy when required
- Fatty acid: form in which fats circulate in the blood and are stored in the liver.
Agave. The very name is exciting, redolent of Mexican deserts and secret herbs.
It comes from the same plant used to sweeten Tequila. It’s on the shelves of your local health food shop in more and more products. Why? And it is a good natural substitute for sugar, maple syrup or honey?
Perhaps if you were trying to save money you’d be interested in its relative sweetness. It’s 50% sweeter than sugar.. but at its prices per pound it’s a serious sweetness to the dollar loser. It’s also far more expensive than equally natural cane sugar.
So.. exactly WHY would you choose gave over sugar? One correspondent of mine accused me of being ‘unnatural’, claiming that “The Aztecs prized the agave as a gift from the gods and used the liquid from its core to flavor foods and drinks.”
One might well respond by asking where the Aztecs are today but that would be a cheap shot.
What amuses me is that somehow my correspondent believes that because Aztecs had the same sugar addiction as us and salved it using Agave, then Agave must be somehow better.
So is it a suitable alternative to sugar if you have say, diabetes, or are overly acidic, or have one or more of the hundreds of acid-related health conditions?
Most agave sweeteners come from the blue agave plant. You don’t get its raw nectar. Much like high-fructose corn syrup, it’s highly processed before you can add it to your tea, top your pancakes with it, or get it in an energy drink, bar, or other product. Yes, as my correspondent said, to make the agave nectar, sap is extracted from the pina, filtered, and heated at a low temperature, which breaks down the carbohydrates into a natural sugar blue agave plant. So now it’s a ‘natural’ sugar, so he suggests that because it’s ‘natural’ it’s better for you. Sorry, friend, just because something is ‘natural’ does not automatically send it to the ‘healthy’ box.
By following the New Alkaline Diet I have personally changed my diet substantially away from the concept of gathering calories from carbs and sugars – particularly sugars, given their proven addictive nature. So the fact that agave has about 60 calories per tablespoon, compared to 40 calories for the same amount of table sugar is of no great concern to me because I try to keep away from all sweeteners.
As a result I enjoy my food more than I ever have in my life, I have overcome my sugar-hit mood swings, and I am eating far less becasue I am not experiencing my past sudden snackaholicism.
So if you have diabetes, is it a good ‘natural’ substitute? It’ something the agave vendors claim, but I think having read what I’ve written so far, the answer is self-evident. We are sold on it with claims that it’s high in fructose and low on the glycemic index, making it a better option than refined sugar. But I can find no research to back that up.
The American Diabetes Association seems to have made its mind up. It has listed agave as a sweetener to limit, along with regular table sugar, brown sugar, honey, maple syrup, and all other sugars.
Liz Applegate, director of sports nutrition at the University of California, Davis, agrees. She says your body doesn’t know where the fructose or glucose comes from, be it fruit, agave, or high-fructose corn syrup; so if you eat too much of it, that’s a problem. I would go even further. There is more evidence coming in almost daily that even artificial sweeteners, once substituted for sucrose and fructose, have exactly the same effect on our body. The drug effect remains.
The simple fact we all shy away from is this: Less Is More With All Added Sweeteners
Agave may be ‘natural’ but it offers no miraculous health benefits, Applegate says. It simply adds sweetness.
Less Is More With All Added Sweeteners, and if you are serious about breaking the acid/inflammation/disease cycle, there’s only one decision you can make.
More on the New Alkaline Diet
Common painkillers such as aspirin and ibuprofen almost double the risk for deep vein thrombosis (DVT) and pulmonary embolism, two lethal conditions.
The NSAIDs (non-steroidal, anti-inflammatory drugs), some of the most common drugs in the world, increase the risk of DVT 1.8 fold, a new study has discovered.
The risk is “significant”, say researchers from Bassett Medical Centre in New York, and doctors should be aware of the risk, especially among patients who already have a history of DVT or venous thromboembolism (VTE).
The researchers made the discovery after they reanalysed six studies, which involved 21,401 cases of VTE.
Ian: I just can’t get my head around the use of painkillers. Admittedly I live a charmed life free of extreme pain so I guess that disqualifies me. But when I hear the results coming from people now accessing molecular hydrogen – often people who had almost decided on surgery to stop the pain – I do wonder what it is that keeps people thinking they should use these sorts of pain killers when the side effects are so often experienced.