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Can H2 Water assist us to slow bone loss?

This scientific study of rats says so. yes, of course, it’s rats, not humans, but as a recovering Osteoporosis sufferer, I looked twice when Isaw this study. Do I wait until there’s a double blind randomised study by a Big Pharma or do I just keep drinking my UltraStream H2 water.

No contest really!

Here’s the details of the study.

Br J Pharmacol. 2013 Mar;168(6):1412-20. doi: 10.1111/bph.12036.

Hydrogen water consumption prevents osteopenia in ovariectomized rats.



Accumulating evidence indicates an important role of oxidative stress in the progression of osteoporosis. Recently, it was demonstrated that hydrogen gas, as a novel antioxidant, could selectively reduce hydroxyl radicals and peroxynitrite anion to exert potent therapeutic antioxidant activity. The aim of the present work was to investigate the effect of hydrogen water (HW) consumption on ovariectomy-induced osteoporosis.


Ovariectomized rats were fed with HW (1.3 ± 0.2 mg·L⁻¹) for 3 months. Then, blood was collected and femur and vertebrae were removed for evaluation of the effect of HW on bone.


HW consumption in ovariectomized rats had no significant effect on oestrogen production, but prevented the reduction of bone mass including bone mineral content and bone mineral density in femur and vertebrae, and preserved mechanical strength including ultimate load, stiffness, and energy, and bone structure including trabecular bone volume fraction, trabecular number, and trabecular thickness in femur, and preserved mechanical strength including ultimate load and stiffness, and bone structure including trabecular bone volume fraction and trabecular number in vertebrae. In addition, treatment with HW abated oxidative stress and suppressed IL-6 and TNF-α mRNA expressions in femur of ovariectomized rats; treatment with HW increased femur endothelial NOS activity and enhanced circulating NO level in ovariectomized rats.


HW consumption prevents osteopenia in ovariectomized rats possibly through the ablation of oxidative stress induced by oestrogen withdrawal.

© 2012 The Authors. British Journal of Pharmacology © 2012 The British Pharmacological Society.

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